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Routine - What It Is, What It Serves for, Side Effects, Sources and Tips

In the last decades, several researches have been carried out to identify natural substances that were present in the plants and could be used in the pharmaceutical industry due to the numerous properties gifts. Many civilizations have already used natural products to heal and treat diseases.

Currently, approximately 60% of the antibiotic and antitumor agents available on the market are made with substances, thus showing the potential of these products and their applications. Routine, for example, is considered one of these bioactive substances, presenting numerous applications.

Let us know what rutin is, know what this substance is for and learn more about its benefits and possible side effects.

What are bioactive substances?

Bioactive compounds are substances in vegetables, fruits and vegetables that can contribute to the proper functioning of the body and increase physical and mental well-being. These substances also aid in the combat and treatment of various diseases.

Polyphenols are among the most studied and known bioactive substances. They are present in fruits like apple, cherry, blackberry, grape, in vegetables and vegetables like broccoli, cauliflower, onion, beet, and also in oilseeds like almonds and walnuts.

Foods containing bioactive substances are called functional foods. These foods contain basic nutritional properties and, in addition, they bring specific health benefits. Many of them are able to regulate blood pressure, prevent premature aging and help in the prevention of diseases such as diabetes, cancer, osteoporosis, among others.

What is routine?

Several studies on the substances present in plants have been carried out over the last decades. In 1930, after a research with oranges, a new substance was identified and isolated from this fruit, It was subsequently classified as a flavonoid and initially called vitamin P, and subsequently routine.

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The so-called flavonoids are bioactive compounds that are part of the polyphenol group. These substances are widely found in fruits, vegetables, vegetables, coffee, teas, wine, cocoa, nuts, among many other foods. Flavonoids help protect plants against oxidative damage and also promote the pigmentation of some foods of the violet, reddish blue and blue colors.

Flavonoids are among the most important groups found in the plant kingdom and these have high antioxidant power, helping in the fight against free radicals and protecting tissues against the action of oxygen. This group of substances is divided into several other smaller groups, among them flavones, anthocyanins, catechins, flavonols, isoflavones, flavonones, chalcones, among others.

Routine is found in a variety of food sources, such as onions, grapes, apples, beverages such as red wine and black tea, in fruit peels citrus fruits, in broccoli, lettuce, some types of wheat, among them buckwheat and buckwheat, some types of beans, tomatoes, among others sources.

Currently, this substance can be found and sold as a food supplement in several specialty stores.

What is the routine for?

There are several applications in the industry for flavonoids. They are widely used as dyes, flavorings and flavolizers. Many researches are carried out on its various benefits and some of them have demonstrated the possibility on the various pharmacological applications for these substances.

Flavonoids can act as antioxidants, vasodilators, anti-inflammatories, and have anticarcinogenic applications and help in the prevention of cardiovascular diseases. Routine studies have shown that this substance also has therapeutic applications, helping to symptoms of lymph vessel insufficiency that are associated with hemorrhagic hypertension.

The routine is also used for the treatment of different bleeding states, in addition to the excessive capillary fragility as it happens in cases of dark circles and varicose veins. This substance acts by inhibiting COMT (Catechol-Oxy-Methyl-Transferase), thus allowing an increase in vascular resistance and inhibitory effect of elastase and hyaluronidase.

These substances, in turn, are natural components present in the connective tissue and when these enzymes are blocked there is an increase in vascular resistance. Another property of rutin and also of many other flavonoids is that it increases the absorption of vitamin C, helping to protect the capillaries, and this vitamin can be used in conjunction with the routine.

Like the various types of flavonoids, rutin has antioxidant properties, helping to block the action of free radicals, antibacterial and antithrombotic (which prevent thrombosis). It also helps in the prevention of various types of cancer, has anti-inflammatory action, and also has vasoprotective properties.

Here are some of the benefits of the routine:

1. Help to lose weight

Several researches have also shown that rutin is slimming and that this happens because of its anti-inflammatory properties. Flavonoids help to reduce inflammation in the body and, in this way, stimulate the decrease in levels of the hormone leptin, which is responsible for increasing appetite.

The high production of leptin by the body is associated with overweight and obesity. Therefore, rutin reduces and stimulates the reduction of leptin levels in the body.

2. Improves the circulatory system

Studies have shown that this flavonoid helps to strengthen and also increase the flexibility of blood vessels, including arteries and capillaries. With the improvement of the circulatory system, the body benefits from numerous other functions, helping to prevent many health problems, such as varicose veins, hemorrhoids, among many other others.

3. Prevents clot formation

Some studies have shown that this flavonoid helps to prevent the formation of blood clots and, thus, stimulates the prevention of health problems such as pulmonary embolism, heart attacks, stroke, thrombosis others.

4. Helps lower cholesterol

Several research has shown evidence that this substance has the ability to reduce the rates of bad cholesterol (LDL) in the blood. It is believed that these results are associated with the antioxidant properties of the routine.

5. Reduces pain caused by arthritis

Some studies have shown that this substance helps reduce the pain caused by arthritis by stimulating the blockade of oxidative stress that occurs in patients with this disease. It is believed that these results are associated with the anti-inflammatory and antioxidant properties of the routine.

Care of the use and possible side effects

When the rutin is used in the amounts found in fruits and vegetables, it is considered safe oral use. However, if it is used in doses above what is naturally found with the use of dietary supplements, it may have side effects. Among the possible symptoms are headaches, stomach pains, flushing, rashes, blurred vision, nervousness, changes in heartbeat, muscle stiffness, among others.

If you experience any of these symptoms, seek immediate medical attention and guidance. It is worth remembering that the use of any substance or supplement should always be performed only with medical pregnant women, nursing mothers, or persons with a history of illness should not make use of this substance.


Rutin is a bioactive substance in fruits and vegetables, containing numerous health benefits, helping to lose weight, reduce bad cholesterol, improve the circulatory system, among many others functions. The use of supplements based on this substance should always be accompanied by a professional as this may generate some side effects.

Additional References:

  • Chua, L. S. (2013, December). A review on plant-based routin extraction methods and their pharmacological activities [Abstract].Journal of Ethnopharmacology, 150(3), 805-817. https://www.ncbi.nlm.nih.gov/pubmed/24184193
  • Prescott, B. (2012, May 9). Flavonoid compound can prevent blood clots.Harvard Gazette. http://news.harvard.edu/gazette/story/2012/05/flavonoid-compound-can-prevent-blood-clots/
  • Sattanathan, K., Dhanapal, C. K., & Manavala, R. (2010, December). LDL lowering properties of rutin in diabetic patients.International Journal of Pharma and Bio Sciences, 1(4), 467-473. http://www.ijpbs.net/issue-4/Ph-56.pdf
  • Sumera, W. (n.d.). Rutin. https://www.drrathresearch.org/images/attachments/education/Phytobiology/Rutin_2015.pdf
  • Ostrakhovitch, E. a., Afanas'ev, I. B. (2001, September 15). Oxidative stress in rheumatoid arthritis leukocytes: Suppression by rutin and other antioxidants and chelators.Biochemistry Pharmacology, 62(6), 743-746. https://www.ncbi.nlm.nih.gov/pubmed/11551519
  • Rutin - WebMD
    http://www.webmd.com/vitamins-supplements/ingredientmono-270-rutin.asp? ctiveingredientid = 270 &
  • http://www.ncbi.nlm.nih.gov/pubmed/24184193
  • http://www.ncbi.nlm.nih.gov/pubmed/22565308

Have you ever heard of rut and its benefits to our health? Do you consume enough food sources of this substance in your diet? Comment below!

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