Azelaic Acid - What It Serves, Before and After, Gel, Bull, Handled and How to Use

Azelaic acid is a compound that can be used to treat various skin conditions. It promises to present anti-inflammatory, antibacterial and antioxidant properties, which together promote the health of the skin through the decrease of the oil, stimulation to the production of collagen and reduction of the aging precocious.

Below, we will explain what azelaic acid is, what forms are available and give you tips on how to use the product.

Azelaic Acid - What is it?

Azelaic acid is a natural substance extracted from products such as whole grains and also produced by microorganisms present on the skin. Any product containing azelaic acid in its composition should have an adequate pH around, (pH close to the skin), which is the optimal pH at which the properties of azelaic acid have an effect.

What is it for

Azelacetic acid is usually used to treat skin problems like acne, melasma, rosacea and in some cases psoriasis. Several studies indicate that the use of azelaic acid to treat these conditions is more effective than other substances available on the market, such as benzoyl peroxide, salicylic acid and tretinoin, for example.

- Acne Treatment

Azelaic acid is considered a medicine for the treatment of mild to moderate acne. It belongs to a class of drugs called dicarboxylic acids. It acts by eliminating the acne-causing bacteria and also acts by decreasing the production of keratin, which makes the environment conducive to bacterial proliferation.

In the treatment of acne, azelaic acid acts as an antibacterial, anti-inflammatory and anti-keratinizing product (it prevents the production of too much keratin, reducing the accumulation of dead skin in the region and preventing the pores).

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Azelaic acid also reduces the amount of free fatty acids in the skin, making the skin an environment unsuitable for excessive growth of bacteria and fungi. This way it is also effective in cases of fungal acne or in the treatment of conditions such as seborrheic dermatitis, folliculitis, dandruff, eczema and psoriasis.

According to scientific research, levels of free fatty acids in the skin are reduced from 1,% to 1,% after only one month of use of azelaic acid.

- Treatment of melasma

Melasma is a skin condition caused by overproduction of melanin, which results in brown discolorations on the skin. Melasma is usually aggravated by unprotected exposure to the sun. Studies indicate that the use of azelaic acid in the treatment of melasma is more effective than the use of hydroquinone, which is a standard treatment for cases of hyperpigmentation related to the higher production of melanin by skin.

Because it is an inhibitor of the tyrosinase substance (involved in the metabolism of melanin), azelaic acid is capable of reducing melanin synthesis, helping in cases of melasma and hyperpigmentation postinflammatory. In addition, the use of azelaic acid does not cause significant side effects.

- Treatment of rosacea

Rosacea is a chronic condition in the skin characterized by erythema or dilated capillaries that are an appearance of constant redness on the skin. There are up to four types of disease manifestation, but the most common are subtypes 1 and 2. Subtype 1 causes only superficial facial redness, while type 2 also includes the presence of pinkish skin pimples.

The FDA approved the use of azelaic acid for the treatment of rosacea. In a scientific study, azelaic acid in gel form was used to control type 2 rosacea during a 6-month study, significantly decreasing erythema and skin lesions. When using antibiotics in combination with azelaic acid, the effectiveness of the treatment increases.

Probably the antibacterial, antioxidant and anti-inflammatory properties of azelaic acid are responsible for the improvement in cases of rosacea.


According to the information in the package insert of azelaic acid used both in the form of gel and in the form of cream, the use of the product must be through topical application to the skin. Contact with eyes and mucosa should be avoided, and if it occurs, it is necessary to wash the region thoroughly with water.

Side effects

The use of azelaic acid is usually quite safe. However, some adverse effects can be observed, such as burning or burning after application and dryness of the skin. The main advantage of using azelaic acid compared to other products available on the market lies in the fact that it does not cause sensitivity to sun exposure like most products.

After opening, the azelaic acid has a validity of 6 months. The use of overdue medication is completely discouraged.

Azelaic acid is not indicated for use in pregnancy because there are not enough studies to guarantee the safety of the product to the fetus.

- Manipulated

Azelaic acid in its engineered version may exhibit higher concentration of the acid per se in the product, generally about 15 to 20% of the acid in the cream or gel composition. However, obtaining it is only done with a prescription prescribed by the dermatologist.

This is because the higher the acid concentration in the product, the greater the chances of skin irritation and damage. Thus, the supervision of a professional is essential.

How to use

The first tip is to test the product on a small portion of the skin and watch for a few minutes if there was any kind of allergic reaction. If there is, it is possible to protect the skin with the use of a neutral moisturizing substance that does not detract from the absorption of azelaic acid.

The skin should be completely clean and dry before application.

  • Cream:The use of the cream is quite simple. On clean, dry skin, apply a portion of about a centimeter of cream and spread all over the face, massaging the skin to improve absorption. Wait for the product to dry before putting any type of makeup or moisturizer on the face.
  • Gel:The indicated one is to use the azelaic acid at the fingertips and to apply it topically on the face previously cleaned massaging carefully the region. The product can be applied up to 2 times a day. In the case of the gel, it is only recommended to pass another product on the face after total drying. The azelaic acid gel promotes better results in relation to the cream. This is because the absorption of the gel through the skin is more effective.
  • Manipulated:The application of 20% azelaic acid once a day is enough to treat the skin. However, because it is more concentrated and sometimes combined with other substances, the use of manipulated azelaic acid should be done exclusively at the dosage indicated by the dermatologist.


In a one-year study involving 1200 patients with acne, about 8% of individuals noticed an improvement in acne after only 35 days of treatment with azelaic acid 15%. After 73 days, that number increased to 9,%. At the end of the treatment, more than 80% of the people involved in the study said they were satisfied with the results.

In most cases, a significant improvement is observed in only 4 weeks of treatment.

Before and after

Next, we separated some images of people who underwent azelaic acid treatment and obtained excellent results on the skin.

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Azelaic acid can be found in any pharmacy. The most easily found version shows the commercial name of Azelan in cream and contains 15% azelaic acid in its composition. The average price of a 30 grams cream is $ 5, 0.

Despite the investment, dermatologists assure that the results obtained with azelaic acid treatment are worth, mainly due to its natural origin and the almost total absence of adverse effects and the benefits of the substance that make your skin beautiful and healthy.

Additional references:


Have you used any azelaic acid product on the skin to treat one of the conditions listed above? Did you have good results? Comment below!

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